Thursday, February 18, 2010

Broccoli Compound Protects Neurons from Dopamine

SFN stimulates the NF-E2-related factor-2 pathway of antioxidant gene
expression in neurons and may protect against neuronal injury relevant to the
aetiology of Parkinson's disease.

CiteULike: Sulforaphane protects cortical neurons against 5-S-cysteinyl-dopamine-induced toxicity through the activation of ERK1/2, Nrf-2 and the upregulation of detoxification enzymes: "Vauzour, D., Buonfiglio, M., Corona, G., Chirafisi, J., Vafeiadou, K., Angeloni, C., Hrelia, S., Hrelia, P., and Spencer, J. P. E. (2010). Sulforaphane protects cortical neurons against 5-s-cysteinyl-dopamine-induced toxicity through the activation of erk1/2, nrf-2 and the upregulation of detoxification enzymes. Molecular Nutrition & Food Research, 9999(9999):NA+."





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